Current Vacancies at National Bioproducts Institute

Job Advert Summary    

• Supports GMP compliant manufacture of pharmaceutical products by ensuring maximum online time of process Utility services supplied to Manufacturing.
• Learn perform routine maintenance on the machines.
• Conduct daily checks on machines and their support services.
• Evaluate and facilitate repairs of plant equipment and identify actions to prevent recurrences.
• Assist in projects associated with new plant and equipment.

Provide cross-functional support.

• Create spares inventory and help with spares stock take.
• Make wiring diagrams
• Complete training needs as laid by institution in order to obtain qualification.

Minimum Requirements    

• N6 or S4 electrical engineering.

Duties & Responsibilities    
Learn the skills required to ensure continued operation of the plant equipment

• Assist in performing routine checks of all equipment and systems for correct operation
• Schedule maintenance activities as defined by the preventative maintenance plan
• Facilitate the calibration of measuring and control instruments according to defined schedules and production requirements
• Maintaining records and schedules for specified plant and equipment

Learn and facilitate repairs of plant equipment and identify actions to prevent recurrences

• Learn to analyse problems and determining required maintenance /repair work to ensure continuity.
• Liaise with third party contractors where repairs are not possible on site
• Track and report on progress of repairs required.

Maintenance

• Co-ordinate maintenance activities on NBI equipment
• Records keeping

Stock Control

• Learn routine stock take of spares
• Commissioning unit operations
• learn execution of validation studies (IQ, OQ, PQ)
• support project Commissioning unit operations work 
• support capacity expansion projects (CAPEX)
• support continuous process improvements
• Supervision of t contractors
• Implementation of SAP change notifications
• Hands-on work

Core Competencies

• Managing Relationships
• Personal Leadership
• Business Impact
• Leading and Influencing Others
• Ability and willingness to learn new things.
• Problem solving 
• Communication skills
• Team work
• Collaboration
• Technical writing 

go to method of application »

Job Advert Summary    

• Supports GMP compliant manufacture of pharmaceutical products by ensuring maximum online time of process Utility services supplied to Manufacturing.
• Learn perform routine maintenance on the machines.
• Conduct daily checks on machines and their support services.
• Evaluate and facilitate repairs of plant equipment and identify actions to prevent recurrences.
• Assist in projects associated with new plant and equipment.

Provide cross-functional support.

• Create spares inventory and help with spares stock take.
• Make wiring diagrams
• Complete training needs as laid by institution in order to obtain qualification.

Minimum Requirements    

• N6 or S4 Mechanical Engineering.

Duties & Responsibilities    
Learn the skills required to ensure continued operation of the plant equipment

• Assist in performing routine checks of all equipment and systems for correct operation
• Schedule maintenance activities as defined by the preventative maintenance plan
• Facilitate the calibration of measuring and control instruments according to defined schedules and production requirements
• Maintaining records and schedules for specified plant and equipment

Learn and facilitate repairs of plant equipment and identify actions to prevent recurrences

• Learn to analyse problems and determining required maintenance /repair work to ensure continuity.
• Liaise with third party contractors where repairs are not possible on site
• Track and report on progress of repairs required.

Maintenance

• Co-ordinate maintenance activities on NBI equipment
• Records keeping

Stock Control

• Learn routine stock take of spares

Commissioning unit operations

• learn execution of validation studies (IQ, OQ, PQ)

Support project Commissioning unit operations work 

• support capacity expansion projects (CAPEX)
• support continuous process improvements
• Supervision of t contractors
• Implementation of SAP change notifications
• Hands-on work

Core Competencies

• Managing Relationships
• Personal Leadership
• Business Impact
• Leading and Influencing Others
• Ability and willingness to learn new things.
• Problem solving 
• Communication Skills
• Teamwork
• Collaboration
• Technical writing

go to method of application »

Job Advert Summary    

• Supports GMP compliant manufacture of pharmaceutical products by ensuring maximum online time of process Utility services supplied to Manufacturing.
• To be trained and obtain trade test in refrigeration mechanic within specified time.
• Conduct daily checks on machines and their support services.
• Evaluate and facilitate repairs of plant equipment and identify actions to prevent recurrences.
• Assist in projects associated with new plant and equipment.
• Provide cross-functional support.
• Create spares inventory and help with spares stock take.
• Make wiring diagrams
• Complete training needs as laid by institution in order to obtain qualification.

Specific Operational Requirements

• The successful candidate will be required to work an 8-hour shift as rostered.
• May be required to work overtime/travel to meet the business needs.
• Must be prepared to work shifts/weekends/public holidays when needed.

Minimum Requirements    

• N6 or S4 electrical or Mechanical engineering.

Duties & Responsibilities    
Learn the skills required to ensure continued operation of the plant equipment

• Assist in performing routine checks of all equipment and systems for correct operation
• Schedule maintenance activities as defined by the preventative maintenance plan
• Facilitate the calibration of measuring and control instruments according to defined schedules and production requirements
• Maintaining records and schedules for specified plant and equipment

Learn and facilitate repairs of plant equipment and identify actions to prevent recurrences

• Learn to analyse problems and determining required maintenance /repair work to ensure continuity.
• Liaise with third party contractors where repairs are not possible on site
• Track and report on progress of repairs required.

Maintenance

• Co-ordinate maintenance activities on NBI equipment
• Records keeping

Commissioning unit operations

• learn execution of validation studies (IQ, OQ, PQ)

Support project Commissioning unit operations work 

• support capacity expansion projects (CAPEX)
• support continuous process improvements
• Supervision of t contractors
• Implementation of SAP change notifications
• Hands-on work

Core Competencies

• Managing Relationships
• Personal Leadership
• Business Impact
• Leading and Influencing Others
• Ability and willingness to learn new things.
• Problem solving and aligning of resources to needs.
• Accepting accountability, clear decision making and communication.
• Can both work independently and seek peer review when needed
• Technical writing and good oral communication skills

go to method of application »

Job Advert Summary    

• To use as an individual, his/her academic background, training and experience to perform immunoassay, protein expression and purifications prescribed for the production and QC analysis of saleable monoclonal antibodies, recombinant antigens, ELISA kits and components.

Key results areas:

• QC testing of ELISA reagents, components and final kits
• Recombinant Antigen Production and quality analysis
• QC analysis of NBI saleable monoclonal antibodies
• Laboratory resourcing and equipment maintenance

Minimum Requirements    

• Essential: BSc in Biochemistry, Microbiology
• Preferred: BSc Honours in Biochemistry, Microbiology
• 2-3 years ELISA experience and
• 2-3 years recombinant protein expression and purification experience

Duties & Responsibilities    

• QC testing of ELISA reagents, components and final kits.
• QC testing of all ELISA reagents, components and final kits during the different production stags.
• Perform QC procedures on the following ELISA components: EPU Coated ELISA plates
• In-process testing on the hyperimmune coated plates. Hyperimmune conjugates
• All ELISA components (2% Bosine, Conjugate Diluent, Sulphuric acid, Chromogenic substrate, Controls and Standards).
• Complete documentation for all kit components, upload results into LIMS and send to QARM analyst for signing off and authorization in LIMS and final release in SAP.
• Complete documentation for final kits and upload into SAP, send to QARM analyst for SAP upload and to Head: DPP for SAP authorization and to internal Auditor for review and Head: QA for final release of the ELISA kits in SAP.
• Perform test and method validations according to internal DPP program.
• Trouble shooting of hyperimmune ELISA kits for QARM to resolve quality issues.

Production and QC testing of recombinant antigens associated with saleable monoclonal antibodies

• Produce recombinant proteins to support monoclonal antibody production of saleable antibodies.
• QC test to validate activity, specificity and coating concentration of produced recombinant antigens

QC analysis of NBI saleable monoclonal antibodies

• Perform QC analysis on purified saleable monoclonal antibodies using sds-page gel electrophoresis and determine the antibody purity by densitometric analysis using gel imaging software.
• Provide mAb purity and gel result documentation to Section Head: Antibody Production to complete final release of NBI monoclonal antibodies.

Laboratory resourcing and equipment maintenance

• Maintain laboratory equipment and cleanliness
• Maintain chemical and operational consumable stock levels.
• Ensure compliance with ISO13485 standards.
• Perform the general housekeeping of the laboratory.

Core Competencies

• Managing Relationships
• Personal Leadership
• Business Impact
• Leading and Influencing others Technical/Professional knowledge and proficiency
• Knowledge of ISO13485 quality system
• Technical/Professional knowledge and proficiency
• Planning and organising
• Attention to Detail and analysis
• Written and verbal communication
• Computer Literacy in MS Office, SAP and LIMS
• Experience in immunoassays, design and trouble-shooting ELISA’s
• Collaboration and teamwork

Closing Date    
2023/09/01